Broad Conditions Favor the Evolution of Phase-Variable Loci

ABSTRACT Simple sequence repeat (SSR) tracts produce stochastic on-off switching, or phase variation, in the expression of a panoply of surface molecules in many bacterial commensals and pathogens. A change to the number of repeats in a tract may alter the phase of the translational reading frame, w...

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Bibliographic Details
Main Authors: M. E. Palmer, M. Lipsitch, E. R. Moxon, C. D. Bayliss
Format: Article
Language:English
Published: American Society for Microbiology 2013-03-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00430-12