A Method to Generate and Rescue Recombinant Adenovirus Devoid of Replication-Competent Particles in Animal-Origin-Free Culture Medium

Adenoviruses are promising vectors for vaccine production and gene therapy. Despite all the efforts in removing animal-derived components such as fetal bovine serum (FBS) during the production of adenovirus vector (AdV), FBS is still frequently employed in the early stages of production. Conventiona...

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Bibliographic Details
Main Authors: Seyyed Mehdy Elahi, Jennifer Jiang, Nazila Nazemi-Moghaddam, Rénald Gilbert
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/15/11/2152