Crucial aspects for maintaining rAAV stability

Crucial aspects for maintaining rAAV stability

Abstract The storage of rAAV vectors for gene therapy applications is critical for ensuring a constant product quality and defined amount of medication at the time of administration. Therefore, we determined the influence of different storage conditions on the physicochemical and biological properti...

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Bibliographic Details
Main Authors: Johannes Lengler, Mia Gavrila, Janina Brandis, Kristina Palavra, Felix Dieringer, Sabine Unterthurner, Felix Fuchsberger, Barbara Kraus, Juan A. Hernandez Bort
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Gene therapy
rAAV8
rAAV9
Stability
Biopotency
Online Access:https://doi.org/10.1038/s41598-024-79369-0

Internet

https://doi.org/10.1038/s41598-024-79369-0

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