Avian IRF1 and IRF7 Play Overlapping and Distinct Roles in Regulating IFN-Dependent and -Independent Antiviral Responses to Duck Tembusu Virus Infection

Avian IRF1 and IRF7 Play Overlapping and Distinct Roles in Regulating IFN-Dependent and -Independent Antiviral Responses to Duck Tembusu Virus Infection

Avian interferon regulatory factors 1 and 7 (IRF1 and IRF7) play important roles in the host’s innate immunity against viral infection. Our previous study revealed that duck tembusu virus (DTMUV) infection of chicken fibroblasts (DF1) and duck embryo fibroblasts (DEFs) induced the expression of a va...

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Bibliographic Details
Main Authors: Chengwei Xiang, Zekun Yang, Ting Xiong, Ting Wang, Jie Yang, Mei Huang, Dingxiang Liu, Ruiai Chen
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Viruses
Subjects:
duck tembusu virus
IRF1
IRF7
antiviral response
nonstructural protein NS2B
Online Access:https://www.mdpi.com/1999-4915/14/7/1506

Internet

https://www.mdpi.com/1999-4915/14/7/1506

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