A New Stereoselective Approach to the Substitution of Allyl Hydroxy Group in <i>para</i>-Mentha-1,2-diol in the Search for New Antiparkinsonian Agents

A New Stereoselective Approach to the Substitution of Allyl Hydroxy Group in <i>para</i>-Mentha-1,2-diol in the Search for New Antiparkinsonian Agents

Two approaches to the synthesis of <i>para</i>-menthene epoxide ((1<i>S</i>,5<i>S</i>,6<i>R</i>)<i>-</i><b>4</b>) are developed. The first approach includes a reaction between chlorohydrin <b>7</b> and NaH in THF. Th...

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Bibliographic Details
Main Authors: Alexandra V. Podturkina, Oleg V. Ardashov, Konstantin P. Volcho, Nariman F. Salakhutdinov
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Molecules
Subjects:
monoterpene
nucleophilic substitution
synthetic methods
Prottremine
epoxide
Online Access:https://www.mdpi.com/1420-3049/28/21/7303

Internet

https://www.mdpi.com/1420-3049/28/21/7303

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