RPS27a and RPL40, Which Are Produced as Ubiquitin Fusion Proteins, Are Not Essential for p53 Signalling

Two of the four human ubiquitin-encoding genes express ubiquitin as an N-terminal fusion precursor polypeptide, with either ribosomal protein (RP) RPS27a or RPL40 at the C-terminus. RPS27a and RPL40 have been proposed to be important for the induction of the tumour suppressor p53 in response to defe...

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Bibliographic Details
Main Authors: Matthew John Eastham, Andria Pelava, Graeme Raymond Wells, Nicholas James Watkins, Claudia Schneider
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/13/6/898