Liver-derived plasminogen mediates muscle stem cell expansion during caloric restriction through the plasminogen receptor Plg-RKT

Liver-derived plasminogen mediates muscle stem cell expansion during caloric restriction through the plasminogen receptor Plg-RKT

Summary: An intriguing effect of short-term caloric restriction (CR) is the expansion of certain stem cell populations, including muscle stem cells (satellite cells), which facilitate an accelerated regenerative program after injury. Here, we utilized the MetRSL274G (MetRS) transgenic mouse to ident...

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Bibliographic Details
Main Authors: Akshay Bareja, David E. Lee, Tricia Ho, Greg Waitt, Lauren H. McKay, Sarah A. Hannou, Melissa C. Orenduff, Kristen M. McGreevy, Alexandra Binder, Calen P. Ryan, Erik J. Soderblom, Daniel W. Belsky, Luigi Ferrucci, Jayanta Kumar Das, Nirad Banskota, Virginia B. Kraus, Janet L. Huebner, William E. Kraus, Kim M. Huffman, Gurpreet S. Baht, Steve Horvath, Robert J. Parmer, Lindsey A. Miles, James P. White
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Cell Reports
Subjects:
CP: Metabolism
CP: Stem cell research
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724002092

Internet

http://www.sciencedirect.com/science/article/pii/S2211124724002092

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