Home-cage behavior in the Stargazer mutant mouse

Abstract In many childhood-onset genetic epilepsies, seizures are accompanied by neurobehavioral impairments and motor disability. In the Stargazer mutant mouse, genetic disruptions of Cacng2 result in absence-like spike-wave seizures, cerebellar gait ataxia and vestibular dysfunction, which limit t...

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Bibliographic Details
Main Authors: Catharina Schirmer, Mark A. Abboud, Samuel C. Lee, John S. Bass, Arindam G. Mazumder, Jessica L. Kamen, Vaishnav Krishnan
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-17015-3