Fas-associated factor 1 mediates NADPH oxidase-induced reactive oxygen species production and proinflammatory responses in macrophages against Listeria infection.

Fas-associated factor 1 is a death-promoting protein that induces apoptosis by interacting with the Fas receptor. Until now, FAF1 was reported to interact potentially with diverse proteins and to function as a negative and/or positive regulator of several cellular possesses. However, the role of FAF...

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Main Authors: Tae-Hwan Kim, Hyun-Cheol Lee, Jae-Hoon Kim, C Y Hewawaduge, Kiramage Chathuranga, W A Gayan Chathuranga, Pathum Ekanayaka, H M S M Wijerathne, Chul-Joong Kim, Eunhee Kim, Jong-Soo Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-08-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008004