KIBRA upregulation increases susceptibility to podocyte injury and glomerular disease progression

KIBRA upregulation increases susceptibility to podocyte injury and glomerular disease progression

Despite recent progress in the identification of mediators of podocyte injury, mechanisms underlying podocyte loss remain poorly understood, and cell-specific therapy is lacking. We previously reported that kidney and brain expressed protein (KIBRA), encoded by WWC1, promotes podocyte injury in vitr...

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Bibliographic Details
Main Authors: Kristin Meliambro, Yanfeng Yang, Marina de Cos, Estefania Rodriguez Ballestas, Caroline Malkin, Jonathan Haydak, John R. Lee, Fadi Salem, Laura H. Mariani, Ronald E. Gordon, John M. Basgen, Huei Hsun Wen, Jia Fu, Evren U. Azeloglu, John Cijiang He, Jenny S. Wong, Kirk N. Campbell
Format: Article
Language:English
Published: American Society for Clinical investigation 2023-04-01
Series:JCI Insight
Subjects:
Cell biology
Nephrology
Online Access:https://doi.org/10.1172/jci.insight.165002

Internet

https://doi.org/10.1172/jci.insight.165002

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