In Silico Prediction of Toxicological and Pharmacokinetic Characteristics of Medicinal Compounds

In Silico Prediction of Toxicological and Pharmacokinetic Characteristics of Medicinal Compounds

Scientific relevance. Studies of the toxicological and pharmacokinetic properties of medicinal compounds are a crucial stage of preclinical research; unsatisfactory results may invalidate further drug development. Therefore, the development of in silico methods for a preliminary pre-experimental ass...

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Bibliographic Details
Main Authors: P. M. Vassiliev, A. V. Golubeva, A. R. Koroleva, M. A. Perfilev, A. N. Kochetkov
Format: Article
Language:Russian
Published: Ministry of Health of the Russian Federation, Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» 2023-12-01
Series:Безопасность и риск фармакотерапии
Subjects:
admet
computer prediction
in silico
toxicological parameters
pharmacokinetic parameters
chemical compounds
medicinal compounds
consensus method
artificial neural networks
Online Access:https://www.risksafety.ru/jour/article/view/380

Internet

https://www.risksafety.ru/jour/article/view/380

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