Tackling new psychoactive substances through metabolomics: UHPLC-HRMS study on natural and synthetic opioids in male and female murine models

Abstract Novel psychoactive substances (NPS) represent a broad class of drugs new to the illicit market that often allow passing drug-screening tests. They are characterized by a variety of structures, rapid transience on the drug scene and mostly unknown metabolic profiles, thus creating an ever-ch...

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Bibliographic Details
Main Authors: Gaia Di Francesco, Camilla Montesano, Flaminia Vincenti, Sabrine Bilel, Giorgia Corli, Greta Petrella, Daniel Oscar Cicero, Adolfo Gregori, Matteo Marti, Manuel Sergi
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-60045-2