MG53 suppresses tumor growth via transcriptional inhibition of KIF11 in pancreatic cancer

MG53 suppresses tumor growth via transcriptional inhibition of KIF11 in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) poses a formidable challenge in oncology due to its limited treatment options and poor long-term survival rates. Our previous work identified MG53, a member of the tripartite motif family protein (TRIM72), as a key player in tissue repair with potential applic...

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Bibliographic Details
Main Authors: Xiao-Liang Wang, Xiangfei He, Tong Gao, Xinyu Zhou, Zobeida Cruz-Monserrate, Allan Tsung, Jianjie Ma, Chuanxi Cai
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Translational Oncology
Subjects:
TRIM72
Nuclear translocation
Cell proliferation
Syngeneic orthotopic transplantation
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523324002456

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http://www.sciencedirect.com/science/article/pii/S1936523324002456

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