Racial disparities in metastatic colorectal cancer outcomes revealed by tumor microbiome and transcriptome analysis with bevacizumab treatment

Racial disparities in metastatic colorectal cancer outcomes revealed by tumor microbiome and transcriptome analysis with bevacizumab treatment

Background: Metastatic colorectal cancer (mCRC) is a heterogeneous disease, often associated with poor outcomes and resistance to therapies. The racial variations in the molecular and microbiological profiles of mCRC patients, however, remain under-explored.Methods: Using RNA-SEQ data, we extracted...

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Bibliographic Details
Main Authors: Lei Feng, Rui Wang, Qian Zhao, Jun Wang, Gang Luo, Chongwen Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Pharmacology
Subjects:
mCRC
transcriptomics
intratumoral microbiome
multi-omics
racial variations
bevacizumab
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1320028/full

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https://www.frontiersin.org/articles/10.3389/fphar.2023.1320028/full

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