NADPH oxidase 4 is required for the generation of macrophage migration inhibitory factor and host defense against Toxoplasma gondii infection

Abstract Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (Nox) are an important family of catalytic enzymes that generate reactive oxygen species (ROS), which mediate the regulation of diverse cellular functions. Although phagocyte Nox2/gp91phox is closely associated with the activation...

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Bibliographic Details
Main Authors: Ji Hye Kim, Jina Lee, Su-Jin Bae, Yeeun Kim, Byung-Joon Park, Jae-Won Choi, Jaeyul Kwon, Guang-Ho Cha, Heon Jong Yoo, Eun-Kyeong Jo, Yun Soo Bae, Young-Ha Lee, Jae-Min Yuk
Format: Article
Language:English
Published: Nature Portfolio 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-06610-4