The environmental enrichment ameliorates chronic unpredictable mild stress-induced depressive-like behaviors and cognitive decline by inducing autophagy-mediated inflammation inhibition

The environmental enrichment ameliorates chronic unpredictable mild stress-induced depressive-like behaviors and cognitive decline by inducing autophagy-mediated inflammation inhibition

Background: People exposed to prolonged chronic unpredictable mild stress (CUMS) are easy to suffer from depression and cognitive impairment. Environmental enrichment (EE) had a beneficial effect on depressive-like and cognition-like behaviors by inhibiting inflammation. However, the specific mechan...

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Bibliographic Details
Main Authors: Linling Xu, Huimin Sun, Chujie Qu, Jun Shen, Changhua Qu, Hao Song, Tian Li, Jiaxin Zheng, Junjian Zhang
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Brain Research Bulletin
Subjects:
Chronic unpredictable mild stress
Environmental enrichment
Depression
Cognition
Autophagy
Inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S0361923022001642

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http://www.sciencedirect.com/science/article/pii/S0361923022001642

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