Genetic association of mosaic loss of chromosome Y with prostate cancer in men of European and East Asian ancestries: a Mendelian randomization study

Background: Genomic instability is a significant hallmark of aging and has a major impact on aging biology. Mosaic loss of chromosome Y (mLOY) in blood cells is a common chromosomal abnormality in aging men and is considered an indicator of genomic instability. Previous studies have indicated a conn...

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Bibliographic Details
Main Authors: Takuro Kobayashi, Tsuyoshi Hachiya, Yoshihiro Ikehata, Shigeo Horie
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Aging
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fragi.2023.1176451/full