The Value of Mouse Models of Rare Diseases: A Spanish Experience

The Value of Mouse Models of Rare Diseases: A Spanish Experience

Animal models are invaluable for biomedical research, especially in the context of rare diseases, which have a very low prevalence and are often complex. Concretely mouse models provide key information on rare disease mechanisms and therapeutic strategies that cannot be obtained by using only altern...

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Bibliographic Details
Main Authors: Silvia Murillo-Cuesta, Rafael Artuch, Fernando Asensio, Pedro de la Villa, Mara Dierssen, Jose Antonio Enríquez, Cristina Fillat, Stéphane Fourcade, Borja Ibáñez, Lluis Montoliu, Eduardo Oliver, Aurora Pujol, Eduardo Salido, Mario Vallejo, Isabel Varela-Nieto
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Genetics
Subjects:
orphan diseases
animal models
preclinical research
novel therapies
ethics
transparency
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.583932/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2020.583932/full

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