Early functional connectivity deficits and progressive microstructural alterations in the TgF344-AD rat model of Alzheimer’s Disease: A longitudinal MRI study

Early functional connectivity deficits and progressive microstructural alterations in the TgF344-AD rat model of Alzheimer’s Disease: A longitudinal MRI study

The development and characterization of new improved animal models is pivotal in Alzheimer's Disease (AD) research, since valid models enable the identification of early pathological processes, which are often not accessible in patients, as well as subsequent target discovery and evaluation. Th...

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Bibliographic Details
Main Authors: Cynthia Anckaerts, Ines Blockx, Priska Summer, Johanna Michael, Julie Hamaide, Christina Kreutzer, Hervé Boutin, Sébastien Couillard-Després, Marleen Verhoye, Annemie Van der Linden
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Neurobiology of Disease
Subjects:
Alzheimer's disease
TgF344-AD
Resting state fMRI
rsfMRI
Diffusion tensor imaging
DTI
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996118307459

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http://www.sciencedirect.com/science/article/pii/S0969996118307459

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