Relationship of apolipoprotein(a) isoform size with clearance and production of lipoprotein(a) in a diverse cohort

Relationship of apolipoprotein(a) isoform size with clearance and production of lipoprotein(a) in a diverse cohort

Lipoprotein(a) [Lp(a)] has two main proteins, apoB100 and apo(a). High levels of Lp(a) confer an increased risk for atherosclerotic cardiovascular disease. Most people have two circulating isoforms of apo(a) differing in their molecular mass, determined by the number of Kringle IV Type 2 repeats. Pr...

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Bibliographic Details
Main Authors: Anastasiya Matveyenko, Nelsa Matienzo, Henry Ginsberg, Renu Nandakumar, Heather Seid, Rajasekhar Ramakrishnan, Steve Holleran, Tiffany Thomas, Gissette Reyes-Soffer
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Journal of Lipid Research
Subjects:
kringle IV Type 2 repeats (KIV-2)
Weighted isoform size (wIS)
Apolipoprotein (a) production
Apolipoprotein (a) fractional clearance
Stable isotope studies
Atherosclerotic cardiovascular disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227523000093

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http://www.sciencedirect.com/science/article/pii/S0022227523000093

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