The inducible secreting TLR5 agonist, CBLB502, enhances the anti-tumor activity of CAR133-NK92 cells in colorectal cancer

Objective: CAR-T/NK cells have had limited success in the treatment of solid tumors, such as colorectal cancer (CRC), in part because of the heterogeneous nature of tumor-associated antigens that lead to antigen-negative relapse after the initial response. This barrier might be overcome by enhancing...

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Bibliographic Details
Main Authors: Xiaohui Wang, Wei Qiu, Haoyu Liu, Min He, Wei He, Zhan Li, Zhiqiang Wu, Xiang Xu, Ping Chen
Format: Article
Language:English
Published: China Anti-Cancer Association 2023-09-01
Series:Cancer Biology & Medicine
Subjects:
Online Access:https://www.cancerbiomed.org/content/20/9/662