Dopamine facilitates the translation of physical exertion into assessments of effort

Abstract Our assessments of effort are critically shaped by experiences of exertion. However, it is unclear how the nervous system transforms physical exertion into assessments of effort. Availability of the neuromodulator dopamine influences features of motor performance and effort-based decision-m...

Full description

Bibliographic Details
Main Authors: Purnima Padmanabhan, Agostina Casamento-Moran, Aram Kim, Anthony J. Gonzalez, Alexander Pantelyat, Ryan T. Roemmich, Vikram S. Chib
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-023-00490-4