Pterostilbene attenuates microglial inflammation and brain injury after intracerebral hemorrhage in an OPA1-dependent manner

Pterostilbene attenuates microglial inflammation and brain injury after intracerebral hemorrhage in an OPA1-dependent manner

Microglial activation and subsequent inflammatory responses are critical processes in aggravating secondary brain injury after intracerebral hemorrhage (ICH). Pterostilbene (3’, 5’-dimethoxy-resveratrol) features antioxidant and anti-inflammation properties and has been proven neuroprotective. In th...

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Bibliographic Details
Main Authors: Yang Wu, Qing Hu, Xiaoliang Wang, Hongbo Cheng, Jiegang Yu, Yang Li, Jianing Luo, Qingjiu Zhang, Jianliang Wu, Gengshen Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Immunology
Subjects:
intracerebral hemorrhage
pterostilbene
neuroinflammation
microglia
mitochondria
OPA1
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1172334/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1172334/full

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