Comprehensive evaluation of the metabolic effects of porcine CRTC3 overexpression on subcutaneous adipocytes with metabolomic and transcriptomic analyses

Comprehensive evaluation of the metabolic effects of porcine CRTC3 overexpression on subcutaneous adipocytes with metabolomic and transcriptomic analyses

Abstract Background Meat quality is largely driven by fat deposition, which is regulated by several genes and signaling pathways. The cyclic adenosine monophosphate (cAMP) -regulated transcriptional coactivator 3 (CRTC3) is a coactivator of cAMP response element binding protein (CREB) that mediates...

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Bibliographic Details
Main Authors: Jiaqi Liu, Jie Li, Wentao Chen, Xintao Xie, Xingang Chu, Teresa G. Valencak, Yizhen Wang, Tizhong Shan
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Journal of Animal Science and Biotechnology
Subjects:
CRTC3
Energy metabolism
Metabolomics
Overexpression
Subcutaneous adipocytes
Transcriptomics
Online Access:https://doi.org/10.1186/s40104-021-00546-6

Internet

https://doi.org/10.1186/s40104-021-00546-6

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