Huanglian Decoction treats Henoch-Schonlein purpura nephritis by inhibiting NF-κB/NLRP3 signaling pathway and reducing renal IgA deposition

Huanglian Decoction treats Henoch-Schonlein purpura nephritis by inhibiting NF-κB/NLRP3 signaling pathway and reducing renal IgA deposition

Abstract Henoch-Schonlein purpura nephritis (HSPN) is a systemic vascular inflammatory disease. Huanglian Decoction (HLD) ameliorates renal injury in nephritis; however, the mechanism of action of HLD on HSPN has not been investigated. This study aimed to investigate the protective mechanism of HLD...

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Bibliographic Details
Main Authors: LIAN HU, LINLIN LI, HONG CHE, BINGJIE ZHAO, LI XIAO, PEIJIA LIU, WENJING YI, SONGSHAN LIU
Format: Article
Language:English
Published: Academia Brasileira de Ciências 2024-04-01
Series:Anais da Academia Brasileira de Ciências
Subjects:
Henoch-Schonlein purpura nephritis
Huanglian Decoction
NF-κB/NLRP3 signaling pathway
IgA deposition
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652024000100706&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652024000100706&lng=en&tlng=en

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