Transfection of an expressive construct including IgG1 and Fv1 genes in ovary cell line for infliximab expression

Background: Infeliximab is a form of chimeric antibody which neutralizes the most important inflammatory cytokine, TNF-a, in inflammatory disorders. The aim of current study was to pilot expression of chimeric infliximab in Chinese Hamster ovary (CHO) cells. Methods: In this research study, pVITRO2...

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Bibliographic Details
Main Authors: Zohreh Sarabinejad, Davoud Nouri Inanlou, Shahram Teimourian
Format: Article
Language:fas
Published: Tehran University of Medical Sciences 2016-04-01
Series:Tehran University Medical Journal
Subjects:
Online Access:http://tumj.tums.ac.ir/browse.php?a_code=A-10-25-5429&slc_lang=en&sid=1