Diagnostic performance of metagenomic next-generation sequencing for the detection of pathogens in cerebrospinal fluid in pediatric patients with central nervous system infection: a systematic review and meta-analysis

Diagnostic performance of metagenomic next-generation sequencing for the detection of pathogens in cerebrospinal fluid in pediatric patients with central nervous system infection: a systematic review and meta-analysis

Abstract Background Detecting pathogens in pediatric central nervous system infection (CNSI) is still a major challenge in medicine. In addition to conventional diagnostic patterns, metagenomic next-generation sequencing (mNGS) shows great potential in pathogen detection. Therefore, we systematicall...

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Bibliographic Details
Main Authors: Sike He, Ying Xiong, Teng Tu, Jiaming Feng, Yu Fu, Xu Hu, Neng Wang, Dapeng Li
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Infectious Diseases
Subjects:
Pediatric infection
Central nervous system infection
Metagenomic next-generation sequencing
Diagnostic performance
Meta-analysis
Online Access:https://doi.org/10.1186/s12879-024-09010-y

Internet

https://doi.org/10.1186/s12879-024-09010-y

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