Prenatal diagnosis and molecular cytogenetic characterization of a de novo 4.858-Mb microdeletion in 15q14 associated with ACTC1 and MEIS2 haploinsufficiency and tetralogy of Fallot

Prenatal diagnosis and molecular cytogenetic characterization of a de novo 4.858-Mb microdeletion in 15q14 associated with ACTC1 and MEIS2 haploinsufficiency and tetralogy of Fallot

Objective: To present prenatal diagnosis and molecular cytogenetic characterization of a de novo 15q14 microdeletion associated with tetralogy of Fallot (TOF). Materials and methods: This was the first pregnancy of a 31-year-old primigravid woman. The pregnancy was uneventful until 23 weeks of gesta...

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Bibliographic Details
Main Authors: Chih-Ping Chen, Chen-Yu Chen, Schu-Rern Chern, Peih-Shan Wu, Yen-Ni Chen, Shin-Wen Chen, Li-Feng Chen, Chien-Wen Yang, Wayseen Wang
Format: Article
Language:English
Published: Elsevier 2016-04-01
Series:Taiwanese Journal of Obstetrics & Gynecology
Subjects:
15q14 microdeletion
ACTC1
MEIS2
prenatal diagnosis
tetralogy of Fallot
Online Access:http://www.sciencedirect.com/science/article/pii/S1028455916000486

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http://www.sciencedirect.com/science/article/pii/S1028455916000486

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