Protein aggregation profile of the human kinome
Protein aggregation into amyloid fibrils is associated with the onset of an increasing number of human disorders, including Alzheimer’s disease, diabetes and some types of cancer. The ability to form toxic amyloids appears to be a property of most polypeptides. Accordingly, it has been proposed that...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2012-11-01
|
Series: | Frontiers in Physiology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00438/full |