Interplay of four types of RNA modification writers revealed distinct tumor microenvironment and biological characteristics in pancreatic cancer

Interplay of four types of RNA modification writers revealed distinct tumor microenvironment and biological characteristics in pancreatic cancer

BackgroundPancreatic cancer (PC) is one of the most lethal malignancies and carries a dismal mortality and morbidity. Four types of RNA modification (namely m6A, m1A, APA and A-to-I) could be catalyzed by distinct enzymatic compounds (“writers”), mediating numerous epigenetic events in carcinogenesi...

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Bibliographic Details
Main Authors: Wenzhe Gao, Dongjie Chen, Jixing Liu, Longjun Zang, Tijun Xiao, Xianlin Zhang, Zheng Li, Hongwei Zhu, Xiao Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
RNA modification writers
tumor microenvironment
pancreatic cancer
molecular classification
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1031184/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1031184/full

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