Read length versus depth of coverage for viral quasispecies reconstruction.

Recent advancements of sequencing technology have opened up unprecedented opportunities in many application areas. Virus samples can now be sequenced efficiently with very deep coverage to infer the genetic diversity of the underlying virus populations. Several sequencing platforms with different un...

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Bibliographic Details
Main Authors: Osvaldo Zagordi, Martin Däumer, Christian Beisel, Niko Beerenwinkel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23056573/?tool=EBI