Differential localization of dengue virus protease affects cell homeostasis and triggers to thrombocytopenia

Summary: Thrombocytopenia is one of the symptoms of many virus infections which is the “hallmark” in the case of dengue virus. In this study, we show the differential localization of existing two forms of dengue virus protease, i.e., NS2BNS3 to the nucleus and NS3 to the nucleus and mitochondria. We...

Full description

Bibliographic Details
Main Authors: Lekha Gandhi, Deepti Maisnam, Deepika Rathore, Preeti Chauhan, Anvesh Bonagiri, Musturi Venkataramana
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422301101X