Post-Operative Accelerated-Hypofractionated Chemoradiation With Volumetric Modulated Arc Therapy and Simultaneous Integrated Boost in Glioblastoma: A Phase I Study (ISIDE-BT-2)

Post-Operative Accelerated-Hypofractionated Chemoradiation With Volumetric Modulated Arc Therapy and Simultaneous Integrated Boost in Glioblastoma: A Phase I Study (ISIDE-BT-2)

BackgroundGlioblastoma Multiforme (GBM) is the most common primary brain cancer and one of the most lethal tumors. Theoretically, modern radiotherapy (RT) techniques allow dose-escalation due to the reduced irradiation of healthy tissues. This study aimed to define the adjuvant maximum tolerated dos...

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Bibliographic Details
Main Authors: Marica Ferro, Milena Ferro, Gabriella Macchia, Savino Cilla, Milly Buwenge, Alessia Re, Carmela Romano, Mariangela Boccardi, Vincenzo Picardi, Silvia Cammelli, Eleonora Cucci, Samantha Mignogna, Liberato Di Lullo, Vincenzo Valentini, Alessio Giuseppe Morganti, Francesco Deodato
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Oncology
Subjects:
glioblastoma multiforme
volumetric modulated arc therapy
simultaneous integrated boost
adjuvant treatment
temozolomide
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.626400/full

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https://www.frontiersin.org/articles/10.3389/fonc.2020.626400/full

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