Innovate therapeutic targets for autoimmune diseases: insights from proteome-wide mendelian randomization and Bayesian colocalization

Innovate therapeutic targets for autoimmune diseases: insights from proteome-wide mendelian randomization and Bayesian colocalization

AbstractBackground Despite growing knowledge regarding the pathogenesis of autoimmune diseases (ADs) onset, the current treatment remains unsatisfactory. This study aimed to identify innovative therapeutic targets for ADs through various analytical approaches.Research design and methods Utilizing Me...

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Bibliographic Details
Main Authors: Qiubai Jin, Feihong Ren, Ping Song
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Autoimmunity
Subjects:
Autoimmune diseases
plasma proteome
therapeutic target
Mendelian randomization
Bayesian co-localization analysis
Online Access:https://www.tandfonline.com/doi/10.1080/08916934.2024.2330392

Internet

https://www.tandfonline.com/doi/10.1080/08916934.2024.2330392

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