IFITM3 restricts virus-induced inflammatory cytokine production by limiting Nogo-B mediated TLR responses

IFITM3 restricts virus-induced inflammatory cytokine production by limiting Nogo-B mediated TLR responses

The effect of IFITM3 on viral pathogenesis is poorly understood. Here, the authors show that IFITM3 restricts cytomegalovirus pathogenesis by reducing Nogo-B-mediated inflammation in response to viral stimuli.

Bibliographic Details
Main Authors: M. Clement, J. L. Forbester, M. Marsden, P. Sabberwal, M. S. Sommerville, D. Wellington, S. Dimonte, S. Clare, K. Harcourt, Z. Yin, L. Nobre, R. Antrobus, B. Jin, M. Chen, S. Makvandi-Nejad, J. A. Lindborg, S. M. Strittmatter, M. P. Weekes, R. J. Stanton, T. Dong, I. R. Humphreys
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-32587-4

Internet

https://doi.org/10.1038/s41467-022-32587-4

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