A haunted beast: Targeting STAT5BN642H in T-Cell Neoplasia

The somatic hot spot mutation STAT5BN642H was found in many T cell leukemia/lymphoma patients. We generated and analyzed a transgenic mouse model with hematopoietic STAT5BN642H expression that caused aggressive T-cell leukemia/lymphomas. Herein, we discuss the scientific merit of our model and its r...

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Bibliographic Details
Main Authors: Ha Thi Thanh Pham, Markus Hengstschläger, Richard Moriggl
Format: Article
Language:English
Published: Taylor & Francis Group 2018-05-01
Series:Molecular & Cellular Oncology
Subjects:
Online Access:http://dx.doi.org/10.1080/23723556.2018.1435181