Self-delivering prodrug-nanoassemblies fabricated by disulfide bond bridged oleate prodrug of docetaxel for breast cancer therapy

Self-delivering prodrug-nanoassemblies fabricated by disulfide bond bridged oleate prodrug of docetaxel for breast cancer therapy

Breast cancer leads to high mortality of women in the world. Docetaxel (DTX) has been widely applied as one of the first-line chemotherapeutic drugs for breast cancer therapy. However, the clinical outcome of DTX is far from satisfaction due to its poor drug delivery efficiency. Herein, a novel disu...

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Bibliographic Details
Main Authors: Shenwu Zhang, Jibin Guan, Mengchi Sun, Dong Zhang, Haotian Zhang, Bingjun Sun, Weiling Guo, Bin Lin, Yongjun Wang, Zhonggui He, Cong Luo, Jin Sun
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Drug Delivery
Subjects:
breast cancer
docetaxel
oleate prodrug
self-assembly
self-delivery
Online Access:http://dx.doi.org/10.1080/10717544.2017.1381201

Internet

http://dx.doi.org/10.1080/10717544.2017.1381201

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