Interaction of the European genotype porcine reproductive and respiratory syndrome virus (PRRSV) with sialoadhesin (CD169/Siglec-1) inhibits alveolar macrophage phagocytosis

<p>Abstract</p> <p>Porcine reproductive and respiratory syndrome virus (PRRSV) is an arterivirus that shows a restricted in vivo tropism for subsets of porcine macrophages, with alveolar macrophages being major target cells. The virus is associated with respiratory problems in pigs...

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Bibliographic Details
Main Authors: De Baere Miet I, Van Gorp Hanne, Delputte Peter L, Nauwynck Hans J
Format: Article
Language:English
Published: BMC 2012-05-01
Series:Veterinary Research
Online Access:http://www.veterinaryresearch.org/content/43/1/47