Interaction of the European genotype porcine reproductive and respiratory syndrome virus (PRRSV) with sialoadhesin (CD169/Siglec-1) inhibits alveolar macrophage phagocytosis

Interaction of the European genotype porcine reproductive and respiratory syndrome virus (PRRSV) with sialoadhesin (CD169/Siglec-1) inhibits alveolar macrophage phagocytosis

<p>Abstract</p> <p>Porcine reproductive and respiratory syndrome virus (PRRSV) is an arterivirus that shows a restricted in vivo tropism for subsets of porcine macrophages, with alveolar macrophages being major target cells. The virus is associated with respiratory problems in pigs...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors:	De Baere Miet I, Van Gorp Hanne, Delputte Peter L, Nauwynck Hans J
Format:	Article
Sprog:	English
Udgivet:	BMC 2012-05-01
Serier:	Veterinary Research
Online adgang:	http://www.veterinaryresearch.org/content/43/1/47

Lignende værker

Porcine sialoadhesin (CD169/Siglec-1) is an endocytic receptor that allows targeted delivery of toxins and antigens to macrophages.
af: Peter L Delputte, et al.
Udgivet: (2011-01-01)

Susceptible cell lines for the production of porcine reproductive and respiratory syndrome virus by stable transfection of sialoadhesin and CD163
af: Delrue Iris, et al.
Udgivet: (2010-06-01)

The M/GP(5) glycoprotein complex of porcine reproductive and respiratory syndrome virus binds the sialoadhesin receptor in a sialic acid-dependent manner.
af: Wander Van Breedam, et al.
Udgivet: (2010-01-01)

Antigen delivery to macrophages using liposomal nanoparticles targeting sialoadhesin/CD169.
af: Weihsu C Chen, et al.
Udgivet: (2012-01-01)

Crystallographic and in silico analysis of the sialoside-binding characteristics of the Siglec sialoadhesin.
af: Zaccai, N, et al.
Udgivet: (2007)

Selection and validation of reference genes for RT-qPCR normalization of porcine alveolar macrophages (PAMs) for PRRSV studies
af: Dayoung Oh, et al.
Udgivet: (2023-05-01)

Development and Characterization of New Species Cross-Reactive Anti-Sialoadhesin Monoclonal Antibodies
af: Marjorie De Schryver, et al.
Udgivet: (2016-03-01)

The transcriptional characteristics of NADC34-like PRRSV in porcine alveolar macrophages
af: Peixin Wang, et al.
Udgivet: (2022)

The transcriptional characteristics of NADC34-like PRRSV in porcine alveolar macrophages
af: Peixin Wang, et al.
Udgivet: (2022-10-01)

Structure-guided design of sialic acid-based Siglec inhibitors and crystallographic analysis in complex with sialoadhesin.
af: Zaccai, N, et al.
Udgivet: (2003)

PRRSV Vaccine Strain-Induced Secretion of Extracellular ISG15 Stimulates Porcine Alveolar Macrophage Antiviral Response against PRRSV
af: Hongbin Liu, et al.
Udgivet: (2020-09-01)

Structural prediction of porcine sialoadhesin V-set Ig-like domain sheds some light on its role in porcine reproductive and respiratory syndrome virus (PRRSV) infection
af: Jie HOU,Rui LI,Hongfang MA,Songlin QIAO,Gaiping ZHANG
Udgivet: (2016-03-01)

Monoclonal Antibodies Targeting Porcine Macrophages Are Able to Inhibit the Cell Entry of Macrophage-Tropic Viruses (PRRSV and ASFV)
af: Shaojie Han, et al.
Udgivet: (2025-01-01)

Blocking porcine sialoadhesin improves extracorporeal porcine liver xenoperfusion with human blood
af: Waldman, J, et al.
Udgivet: (2013)

Blocking porcine sialoadhesin improves extracorporeal porcine liver xenoperfusion with human blood.
af: Waldman, J, et al.
Udgivet: (2013)

Porcine interferon lambda 3 (IFN-λ3) shows potent anti-PRRSV activity in primary porcine alveolar macrophages (PAMs)
af: Jun Zhao, et al.
Udgivet: (2020-10-01)

Preferential use of Siglec-1 or Siglec-10 by type 1 and type 2 PRRSV strains to infect PK15S1–CD163 and PK15S10–CD163 cells
af: Jiexiong Xie, et al.
Udgivet: (2018-07-01)

Myeloid CD169/Siglec1: An immunoregulatory biomarker in viral disease
af: Silva Herzog, et al.
Udgivet: (2022-09-01)

The role of Siglec-1 and SR-BI interaction in the phagocytosis of oxidized low density lipoprotein by macrophages.
af: Yi-song Xiong, et al.
Udgivet: (2013-01-01)

Unveiling Shared Immune Responses in Porcine Alveolar Macrophages during ASFV and PRRSV Infection Using Single-Cell RNA-seq
af: Bo Jiang, et al.
Udgivet: (2024-03-01)

Transcriptional Immune Signatures of Alveolar Macrophages and the Impact of the NLRP3 Inflammasome on Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Replication
af: Julie A. Hicks, et al.
Udgivet: (2020-11-01)

Identification of Differentially Expressed Non-coding RNA in Porcine Alveolar Macrophages from Tongcheng and Large White Pigs Responded to PRRSV
af: Yueran Zhen, et al.
Udgivet: (2018-10-01)

Sialoadhesin (CD169) expression in CD14+ cells is upregulated early after HIV-1 infection and increases during disease progression.
af: Antoinette C van der Kuyl, et al.
Udgivet: (2007-01-01)

Porcine sialoadhesin suppresses type I interferon production to support porcine reproductive and respiratory syndrome virus infection
af: Yingqi Liu, et al.
Udgivet: (2020-02-01)

Susceptibility of perivenous macrophages to PRRSV-1 subtype 1 LV and PRRSV-1 subtype 3 Lena using a new vein explant model
af: Shaojie Han, et al.
Udgivet: (2023-07-01)

Evaluation of porcine GM-CSF during PRRSV infection in vitro and in vivo indicating a protective role of GM-CSF related with M1 biased activation in alveolar macrophage during PRRSV infection
af: Qi Ji, et al.
Udgivet: (2022-10-01)

Integrative transcriptomic profiling of mRNA, miRNA, circRNA, and lncRNA in alveolar macrophages isolated from PRRSV-infected porcine
af: Ouyang Peng, et al.
Udgivet: (2023-08-01)

Recombinant Antigen of Type 2 Porcine Reproductive and Respiratory Syndrome Virus (PRRSV-2) Promotes M1 Repolarization of Porcine Alveolar Macrophages and Th1 Type Response
af: Rika Wahyuningtyas, et al.
Udgivet: (2021-09-01)

Proximity Labeling and Genetic Screening Reveal that DSG2 is a Counter Receptor of Siglec‐9 and Suppresses Macrophage Phagocytosis
af: Ying Wu, et al.
Udgivet: (2025-03-01)

Interaction between Porcine Alveolar Macrophage-Tang Cells and <i>Streptococcus suis</i> Strains of Different Virulence: Phagocytosis and Apoptosis
af: Siqi Li, et al.
Udgivet: (2023-01-01)

Sialoadhesin-dependent susceptibility and replication of porcine reproductive and respiratory syndrome viruses in CD163-expressing cells
af: Hyun-Ji Lee, et al.
Udgivet: (2024-12-01)

Decreased expression of a phagocytic receptor Siglec-1 on alveolar macrophages in chronic obstructive pulmonary disease
af: Atsushi Tanno, et al.
Udgivet: (2020-01-01)

Highly Pathogenic PRRSV-Infected Alveolar Macrophages Impair the Function of Pulmonary Microvascular Endothelial Cells
af: Weifeng Sun, et al.
Udgivet: (2022-02-01)

SIGLEC1 (CD169): a marker of active neuroinflammation in the brain but not in the blood of multiple sclerosis patients
af: Lennard Ostendorf, et al.
Udgivet: (2021-05-01)

Sialic acid recognition by sialoadhesin and related lectins
af: Vinson, M, et al.
Udgivet: (1997)

In vivo imaging of retrovirus infection reveals a role for Siglec-1/CD169 in multiple routes of transmission
af: Kelsey A Haugh, et al.
Udgivet: (2021-07-01)

MiR-320 inhibits PRRSV replication by targeting PRRSV ORF6 and porcine CEBPB
af: Xiaoxiao Gao, et al.
Udgivet: (2024-05-01)

Sialic acids in pancreatic cancer cells drive tumour-associated macrophage differentiation via the Siglec receptors Siglec-7 and Siglec-9
af: Ernesto Rodriguez, et al.
Udgivet: (2021-02-01)

Characterization of human sialoadhesin, a sialic acid binding receptor expressed by resident and inflammatory macrophage populations.
af: Hartnell, A, et al.
Udgivet: (2001)

Structural basis of sialoadhesin-mediated cell-cell interactions
af: Crocker, P, et al.
Udgivet: (1997)