Interaction of the European genotype porcine reproductive and respiratory syndrome virus (PRRSV) with sialoadhesin (CD169/Siglec-1) inhibits alveolar macrophage phagocytosis
<p>Abstract</p> <p>Porcine reproductive and respiratory syndrome virus (PRRSV) is an arterivirus that shows a restricted in vivo tropism for subsets of porcine macrophages, with alveolar macrophages being major target cells. The virus is associated with respiratory problems in pigs...
Päätekijät: | De Baere Miet I, Van Gorp Hanne, Delputte Peter L, Nauwynck Hans J |
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Aineistotyyppi: | Artikkeli |
Kieli: | English |
Julkaistu: |
BMC
2012-05-01
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Sarja: | Veterinary Research |
Linkit: | http://www.veterinaryresearch.org/content/43/1/47 |
Samankaltaisia teoksia
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The M/GP(5) glycoprotein complex of porcine reproductive and respiratory syndrome virus binds the sialoadhesin receptor in a sialic acid-dependent manner.
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Antigen delivery to macrophages using liposomal nanoparticles targeting sialoadhesin/CD169.
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Crystallographic and in silico analysis of the sialoside-binding characteristics of the Siglec sialoadhesin.
Tekijä: Zaccai, N, et al.
Julkaistu: (2007)