Considerations in Adapting Clinical Trial Design
The concept of adaptation of trial design during the course of a clinical trial has recently drawn much interest from the pharmaceutical industry. The interest arises partly because statistical decision trees employed to address multiple complex clinical hypotheses within a clinical trial are increa...
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Format: | Article |
Language: | English |
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Elsevier
2008-12-01
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Series: | Journal of the Formosan Medical Association |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S0929664609600048 |