A Strength Endurance Exercise Paradigm Mitigates Deficits in Hypoglossal-Tongue Axis Function, Strength, and Structure in a Rodent Model of Hypoglossal Motor Neuron Degeneration

A Strength Endurance Exercise Paradigm Mitigates Deficits in Hypoglossal-Tongue Axis Function, Strength, and Structure in a Rodent Model of Hypoglossal Motor Neuron Degeneration

The tongue plays a crucial role in the swallowing process, and impairment can lead to dysphagia, particularly in motor neuron diseases (MNDs) resulting in hypoglossal-tongue axis degeneration (e.g., amyotrophic lateral sclerosis and progressive bulbar palsy). This study utilized our previously estab...

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Bibliographic Details
Main Authors: Erika R. Murphy, Rebecca Thompson, Kate L. Osman, Chandler Haxton, Margaret Brothers, Li Lee, Kristen Warncke, Catherine L. Smith, Amy N. Keilholz, Ali Hamad, Mojgan Golzy, Filiz Bunyak, Lixin Ma, Nicole L. Nichols, Teresa E. Lever
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Neuroscience
Subjects:
motor neuron disease (MND)
hypoglossal
tongue
dysphagia
exercise
rodent model
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.869592/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2022.869592/full

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