Uncovering lipopolysaccharide regulation in bacteria via the critical lipid binding tunnel of YciS/YciM

Uncovering lipopolysaccharide regulation in bacteria via the critical lipid binding tunnel of YciS/YciM

Summary: Gram-negative bacteria contain an asymmetric outer membrane, in which the outer leaflet is composed of lipopolysaccharide (LPS). LPS, a drug target of polymyxin, plays an essential role in drug resistance, biofilm formation, and pathogenesis. An important inner membrane protein, YciM, may b...

Full description

Bibliographic Details
Main Authors: Lina Yan, Haohao Dong, Huanyu Li, Xingyu Liu, Zixin Deng, Changjiang Dong, Zhengyu Zhang
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:iScience
Subjects:
Biological sciences
Molecular biology
Microbiology
Bacteriology
Structural biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222012603

Internet

http://www.sciencedirect.com/science/article/pii/S2589004222012603

Similar Items