Disease-associated astrocytes and microglia markers are upregulated in mice fed high fat diet

Abstract High-fat diet (HFD) is associated with Alzheimer’s disease (AD) and type 2 diabetes risk, which share features such as insulin resistance and amylin deposition. We examined gene expression associated with astrocytes and microglia since dysfunction of these cell types is implicated in AD pat...

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Bibliographic Details
Main Authors: Li Lin, Rashmita Basu, Debolina Chatterjee, Andrew T. Templin, Jonathan N. Flak, Travis S. Johnson
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-39890-0