ATF2-driven osteogenic activity of enoxaparin sodium-loaded polymethylmethacrylate bone cement in femoral defect regeneration

ATF2-driven osteogenic activity of enoxaparin sodium-loaded polymethylmethacrylate bone cement in femoral defect regeneration

Abstract Background Polymethylmethacrylate (PMMA) bone cement loaded with enoxaparin sodium (PMMA@ES) has been increasingly highlighted to affect the bone repair of bone defects, but the molecular mechanisms remain unclear. We addressed this issue by identifying possible molecular mechanisms of PMMA...

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Bibliographic Details
Main Authors: Luobin Ding, Kangning Hao, Linchao Sang, Xiaoyu Shen, Ce Zhang, Dehao Fu, Xiangbei Qi
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Osteogenic differentiation
Bone marrow mesenchymal stem cells
Femoral defect regeneration
Femoral defect repair
Polymethylmethacrylate bone cement
Enoxaparin sodium
Online Access:https://doi.org/10.1186/s13018-023-04017-8

Internet

https://doi.org/10.1186/s13018-023-04017-8

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