Dynamical consequences of bandpass feedback loops in a bacterial phosphorelay.

Under conditions of nutrient limitation, Bacillus subtilis cells terminally differentiate into a dormant spore state. Progression to sporulation is controlled by a genetic circuit consisting of a phosphorelay embedded in multiple transcriptional feedback loops, which is used to activate the master r...

Full description

Bibliographic Details
Main Authors: Shaunak Sen, Jordi Garcia-Ojalvo, Michael B Elowitz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3182994?pdf=render