Dynamical consequences of bandpass feedback loops in a bacterial phosphorelay.
Under conditions of nutrient limitation, Bacillus subtilis cells terminally differentiate into a dormant spore state. Progression to sporulation is controlled by a genetic circuit consisting of a phosphorelay embedded in multiple transcriptional feedback loops, which is used to activate the master r...
Main Authors: | Shaunak Sen, Jordi Garcia-Ojalvo, Michael B Elowitz |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3182994?pdf=render |
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