Identification of Efflux Substrates Using a Riboswitch-Based Reporter in Pseudomonas aeruginosa

Identification of Efflux Substrates Using a Riboswitch-Based Reporter in Pseudomonas aeruginosa

ABSTRACT Pseudomonas aeruginosa is intrinsically resistant to many classes of antibiotics, reflecting the restrictive nature of its outer membrane and the action of its numerous efflux systems. However, the dynamics of compound uptake, retention, and efflux in this bacterium remain incompletely unde...

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Bibliographic Details
Main Authors: Verónica Urdaneta-Páez, Randy Hamchand, Karen Anthony, Jason Crawford, Alan G. Sutherland, Barbara I. Kazmierczak
Format: Article
Language:English
Published: American Society for Microbiology 2023-04-01
Series:mSphere
Subjects:
Pseudomonas aeruginosa
antimicrobial resistance
drug efflux
Online Access:https://journals.asm.org/doi/10.1128/msphere.00069-23

Internet

https://journals.asm.org/doi/10.1128/msphere.00069-23

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