Silencing the enhancer of zeste homologue 2, Ezh2, represses axon regeneration of dorsal root ganglion neurons

Silencing the enhancer of zeste homologue 2, Ezh2, represses axon regeneration of dorsal root ganglion neurons

Recovery from injury to the peripheral nervous system is different from that of the central nervous system in that it can lead to gene reprogramming that can induce the expression of a series of regeneration-associated genes. This eventually leads to axonal regeneration of injured neurons. Although...

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Bibliographic Details
Main Authors: Ting-Ting Guo, Ying Zhao, Wei-Xiao Huang, Tao Zhang, Li-Li Zhao, Xiao-Song Gu, Song-Lin Zhou
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Neural Regeneration Research
Subjects:
axon regeneration; dorsal root ganglion neurons; ezh2; ib4; laser capture microscopy; nf160/200; quantitative reverse transcription-polymerase chain reaction; sciatic nerve crush; scrna-seq; sirna
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2022;volume=17;issue=7;spage=1518;epage=1525;aulast=Guo

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2022;volume=17;issue=7;spage=1518;epage=1525;aulast=Guo

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