H1 Hemagglutinin Priming Provides Long-Lasting Heterosubtypic Immunity against H5N1 Challenge in the Mouse Model

ABSTRACT Influenza virus infections leave a signature of immune memory that influences future responses to infections with antigenically related strains. It has been hypothesized that the first exposure in life to H1N1 influenza virus imprints the host immune system, potentially resulting in protect...

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Bibliographic Details
Main Authors: Juan Manuel Carreño, Shirin Strohmeier, Ericka Kirkpatrick Roubidoux, Rong Hai, Peter Palese, Florian Krammer
Format: Article
Language:English
Published: American Society for Microbiology 2020-12-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mBio.02090-20